{"id":1540,"date":"2021-10-25T13:51:10","date_gmt":"2021-10-25T11:51:10","guid":{"rendered":"http:\/\/cytomorpholab.com\/?page_id=1540"},"modified":"2025-08-05T23:33:08","modified_gmt":"2025-08-05T21:33:08","slug":"research","status":"publish","type":"page","link":"http:\/\/cytomorpholab.com\/index.php\/research\/","title":{"rendered":"Research &#8211; In Vitro"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"1540\" class=\"elementor elementor-1540\">\n\t\t\t\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-8f8710d elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"8f8710d\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-2b0754c\" data-id=\"2b0754c\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-b70b042 elementor-widget elementor-widget-heading\" data-id=\"b70b042\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.18.0 - 20-12-2023 *\/\n.elementor-heading-title{padding:0;margin:0;line-height:1}.elementor-widget-heading .elementor-heading-title[class*=elementor-size-]>a{color:inherit;font-size:inherit;line-height:inherit}.elementor-widget-heading .elementor-heading-title.elementor-size-small{font-size:15px}.elementor-widget-heading .elementor-heading-title.elementor-size-medium{font-size:19px}.elementor-widget-heading .elementor-heading-title.elementor-size-large{font-size:29px}.elementor-widget-heading .elementor-heading-title.elementor-size-xl{font-size:39px}.elementor-widget-heading .elementor-heading-title.elementor-size-xxl{font-size:59px}<\/style><h2 class=\"elementor-heading-title elementor-size-default\">Research<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-dc2b7e7 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"dc2b7e7\" data-element_type=\"section\" data-settings=\"{&quot;motion_fx_motion_fx_scrolling&quot;:&quot;yes&quot;,&quot;motion_fx_devices&quot;:[&quot;desktop&quot;,&quot;tablet&quot;,&quot;mobile&quot;]}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-9280fc5\" data-id=\"9280fc5\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-2c0a243 elementor-widget__width-initial elementor-widget elementor-widget-button\" data-id=\"2c0a243\" data-element_type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-lg\" href=\"http:\/\/cytomorpholab.com\/index.php\/research\/\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-text\">IN VITRO<\/span>\n\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-65ca805\" data-id=\"65ca805\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-7a45aab elementor-widget__width-inherit elementor-widget elementor-widget-button\" data-id=\"7a45aab\" data-element_type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-xl\" href=\"http:\/\/cytomorpholab.com\/index.php\/research-in-cells\/\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-text\">IN CELLS<\/span>\n\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-fc919c1\" data-id=\"fc919c1\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-0b82517 elementor-align-center elementor-widget__width-initial elementor-widget elementor-widget-button\" data-id=\"0b82517\" data-element_type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-lg\" href=\"http:\/\/cytomorpholab.com\/index.php\/research-tools\/\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-text\">TOOLS<\/span>\n\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-e3a2f4a elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"e3a2f4a\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-75c5d1d\" data-id=\"75c5d1d\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-08a20d3 elementor-widget elementor-widget-heading\" data-id=\"08a20d3\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">In Vitro<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-e026bbe elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"e026bbe\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-905589c\" data-id=\"905589c\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-e0fcdb2 elementor-widget elementor-widget-heading\" data-id=\"e0fcdb2\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">Actin and Microtubule Networks Geometry\n<\/h4>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-3f30247 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"3f30247\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-6c1a22a\" data-id=\"6c1a22a\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-3781fed elementor-widget elementor-widget-text-editor\" data-id=\"3781fed\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.18.0 - 20-12-2023 *\/\n.elementor-widget-text-editor.elementor-drop-cap-view-stacked .elementor-drop-cap{background-color:#69727d;color:#fff}.elementor-widget-text-editor.elementor-drop-cap-view-framed .elementor-drop-cap{color:#69727d;border:3px solid;background-color:transparent}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap{margin-top:8px}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap-letter{width:1em;height:1em}.elementor-widget-text-editor .elementor-drop-cap{float:left;text-align:center;line-height:1;font-size:50px}.elementor-widget-text-editor .elementor-drop-cap-letter{display:inline-block}<\/style>\t\t\t\t<div style=\"direction: ltr;\">\n<div style=\"direction: ltr; margin-top: 0in; margin-left: 0in;\">\n<div style=\"direction: ltr; margin-top: 0in; margin-left: 0in;\">\n<h4>Actin networks<\/h4>\nActin is an asymmetric protein that can self-assemble to form polarized actin filaments. Actin filaments can interact to form actin networks. Actin networks can self-organize into two main types of structures in cells: bundles (or fibers) made of aligned long filaments and meshworks made of branched and intermingled short filaments.\n\nOur aim is to reconstitute both and investigate : 1- how the spatial distribution of actin nucleators directs the growth and assembly of filaments to form defined network geometries in 2D and 3D, 2- how the contraction and disassembly processes regulate networks turn-over and permanent renewal.\n\nIn both cases we try to relate network dynamics to its physical properties and the eventual production of mechanical forces. A particular attention is devoted to the study of the role of actin network geometry and size.\n\n<\/div>\n<\/div>\n<\/div>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-f45b1d4 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"f45b1d4\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-9586778\" data-id=\"9586778\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-aa66baf elementor-widget elementor-widget-image\" data-id=\"aa66baf\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.18.0 - 20-12-2023 *\/\n.elementor-widget-image{text-align:center}.elementor-widget-image a{display:inline-block}.elementor-widget-image a img[src$=\".svg\"]{width:48px}.elementor-widget-image img{vertical-align:middle;display:inline-block}<\/style>\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" width=\"293\" height=\"293\" src=\"http:\/\/cytomorpholab.com\/wp-content\/uploads\/2021\/10\/Actin-array.jpg\" class=\"attachment-large size-large wp-image-1569\" alt=\"\" srcset=\"http:\/\/cytomorpholab.com\/wp-content\/uploads\/2021\/10\/Actin-array.jpg 293w, http:\/\/cytomorpholab.com\/wp-content\/uploads\/2021\/10\/Actin-array-150x150.jpg 150w\" sizes=\"(max-width: 293px) 100vw, 293px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-51950a6\" data-id=\"51950a6\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-bc41172 elementor-widget elementor-widget-image\" data-id=\"bc41172\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img width=\"293\" height=\"293\" src=\"http:\/\/cytomorpholab.com\/wp-content\/uploads\/2021\/10\/Actin-Ring-Contraction.jpg\" class=\"attachment-large size-large wp-image-1565\" alt=\"\" srcset=\"http:\/\/cytomorpholab.com\/wp-content\/uploads\/2021\/10\/Actin-Ring-Contraction.jpg 293w, http:\/\/cytomorpholab.com\/wp-content\/uploads\/2021\/10\/Actin-Ring-Contraction-150x150.jpg 150w\" sizes=\"(max-width: 293px) 100vw, 293px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-8608b08\" data-id=\"8608b08\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-a3f09d6 elementor-widget elementor-widget-image\" data-id=\"a3f09d6\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img width=\"293\" height=\"293\" src=\"http:\/\/cytomorpholab.com\/wp-content\/uploads\/2021\/10\/Actin-Star.jpg\" class=\"attachment-large size-large wp-image-1566\" alt=\"\" srcset=\"http:\/\/cytomorpholab.com\/wp-content\/uploads\/2021\/10\/Actin-Star.jpg 293w, http:\/\/cytomorpholab.com\/wp-content\/uploads\/2021\/10\/Actin-Star-150x150.jpg 150w\" sizes=\"(max-width: 293px) 100vw, 293px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-b7a25cb elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"b7a25cb\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-cb3192e\" data-id=\"cb3192e\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-0a59882 elementor-widget elementor-widget-image\" data-id=\"0a59882\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" width=\"293\" height=\"293\" src=\"http:\/\/cytomorpholab.com\/wp-content\/uploads\/2021\/10\/Actin-Sun.jpg\" class=\"attachment-large size-large wp-image-1567\" alt=\"\" srcset=\"http:\/\/cytomorpholab.com\/wp-content\/uploads\/2021\/10\/Actin-Sun.jpg 293w, http:\/\/cytomorpholab.com\/wp-content\/uploads\/2021\/10\/Actin-Sun-150x150.jpg 150w\" sizes=\"(max-width: 293px) 100vw, 293px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-f5b86b1\" data-id=\"f5b86b1\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-2745231 elementor-widget elementor-widget-image\" data-id=\"2745231\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" width=\"293\" height=\"293\" src=\"http:\/\/cytomorpholab.com\/wp-content\/uploads\/2021\/10\/Actin-Lamellipodium.jpg\" class=\"attachment-large size-large wp-image-1570\" alt=\"\" srcset=\"http:\/\/cytomorpholab.com\/wp-content\/uploads\/2021\/10\/Actin-Lamellipodium.jpg 293w, http:\/\/cytomorpholab.com\/wp-content\/uploads\/2021\/10\/Actin-Lamellipodium-150x150.jpg 150w\" sizes=\"(max-width: 293px) 100vw, 293px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-a11fa13\" data-id=\"a11fa13\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-792c1aa elementor-widget elementor-widget-image\" data-id=\"792c1aa\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" width=\"293\" height=\"293\" src=\"http:\/\/cytomorpholab.com\/wp-content\/uploads\/2021\/10\/Self-Assembled-Electrical-Connections.jpg\" class=\"attachment-large size-large wp-image-1568\" alt=\"\" srcset=\"http:\/\/cytomorpholab.com\/wp-content\/uploads\/2021\/10\/Self-Assembled-Electrical-Connections.jpg 293w, http:\/\/cytomorpholab.com\/wp-content\/uploads\/2021\/10\/Self-Assembled-Electrical-Connections-150x150.jpg 150w\" sizes=\"(max-width: 293px) 100vw, 293px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-54c8ae7 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"54c8ae7\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-4e21dce\" data-id=\"4e21dce\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-c16e67b elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"c16e67b\" data-element_type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.18.0 - 20-12-2023 *\/\n.elementor-widget-divider{--divider-border-style:none;--divider-border-width:1px;--divider-color:#0c0d0e;--divider-icon-size:20px;--divider-element-spacing:10px;--divider-pattern-height:24px;--divider-pattern-size:20px;--divider-pattern-url:none;--divider-pattern-repeat:repeat-x}.elementor-widget-divider .elementor-divider{display:flex}.elementor-widget-divider .elementor-divider__text{font-size:15px;line-height:1;max-width:95%}.elementor-widget-divider .elementor-divider__element{margin:0 var(--divider-element-spacing);flex-shrink:0}.elementor-widget-divider .elementor-icon{font-size:var(--divider-icon-size)}.elementor-widget-divider .elementor-divider-separator{display:flex;margin:0;direction:ltr}.elementor-widget-divider--view-line_icon .elementor-divider-separator,.elementor-widget-divider--view-line_text .elementor-divider-separator{align-items:center}.elementor-widget-divider--view-line_icon .elementor-divider-separator:after,.elementor-widget-divider--view-line_icon .elementor-divider-separator:before,.elementor-widget-divider--view-line_text .elementor-divider-separator:after,.elementor-widget-divider--view-line_text .elementor-divider-separator:before{display:block;content:\"\";border-bottom:0;flex-grow:1;border-top:var(--divider-border-width) var(--divider-border-style) var(--divider-color)}.elementor-widget-divider--element-align-left .elementor-divider .elementor-divider-separator>.elementor-divider__svg:first-of-type{flex-grow:0;flex-shrink:100}.elementor-widget-divider--element-align-left .elementor-divider-separator:before{content:none}.elementor-widget-divider--element-align-left .elementor-divider__element{margin-left:0}.elementor-widget-divider--element-align-right .elementor-divider .elementor-divider-separator>.elementor-divider__svg:last-of-type{flex-grow:0;flex-shrink:100}.elementor-widget-divider--element-align-right .elementor-divider-separator:after{content:none}.elementor-widget-divider--element-align-right .elementor-divider__element{margin-right:0}.elementor-widget-divider:not(.elementor-widget-divider--view-line_text):not(.elementor-widget-divider--view-line_icon) .elementor-divider-separator{border-top:var(--divider-border-width) var(--divider-border-style) var(--divider-color)}.elementor-widget-divider--separator-type-pattern{--divider-border-style:none}.elementor-widget-divider--separator-type-pattern.elementor-widget-divider--view-line .elementor-divider-separator,.elementor-widget-divider--separator-type-pattern:not(.elementor-widget-divider--view-line) .elementor-divider-separator:after,.elementor-widget-divider--separator-type-pattern:not(.elementor-widget-divider--view-line) .elementor-divider-separator:before,.elementor-widget-divider--separator-type-pattern:not([class*=elementor-widget-divider--view]) .elementor-divider-separator{width:100%;min-height:var(--divider-pattern-height);-webkit-mask-size:var(--divider-pattern-size) 100%;mask-size:var(--divider-pattern-size) 100%;-webkit-mask-repeat:var(--divider-pattern-repeat);mask-repeat:var(--divider-pattern-repeat);background-color:var(--divider-color);-webkit-mask-image:var(--divider-pattern-url);mask-image:var(--divider-pattern-url)}.elementor-widget-divider--no-spacing{--divider-pattern-size:auto}.elementor-widget-divider--bg-round{--divider-pattern-repeat:round}.rtl .elementor-widget-divider .elementor-divider__text{direction:rtl}.e-con-inner>.elementor-widget-divider,.e-con>.elementor-widget-divider{width:var(--container-widget-width,100%);--flex-grow:var(--container-widget-flex-grow)}<\/style>\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-a966050 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"a966050\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-7fd87fc\" data-id=\"7fd87fc\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-adc67cf elementor-widget elementor-widget-text-editor\" data-id=\"adc67cf\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div style=\"direction: ltr;\">\n<div style=\"direction: ltr; margin-top: 0in; margin-left: 0in;\">\n<div style=\"direction: ltr; margin-top: 0in; margin-left: 0in;\">\n<h4>Microtubule networks<\/h4>\nSimilar to the formation of actin filaments from the self-assembly of actin monomers, tubulin forms asymmetric dimers that can self-assemble into microtubules. Compared with actin filaments, microtubules are much more rigid, and almost straight in the dimensions of a single cell. Microtubules can sustain much higher\ncompression forces than actin filament but are not as numerous as actin filaments. In most animal cells, the MT network forms as an aster in which microtubules radiate from the microtubule organizing center (MTOC). As cells divide, the MTOC is duplicated and the network forms a bipolar spindle. Our aim is to investigate the\nrole of microtubule mechanics and microtubule-associated proteins in the establishment of the various microtubule network architectures during interphase and mitosis.\n\n<\/div>\n<\/div>\n<\/div>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-220f443 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"220f443\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-118fd26\" data-id=\"118fd26\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-ba05bf1 elementor-widget elementor-widget-image\" data-id=\"ba05bf1\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" width=\"293\" height=\"293\" src=\"http:\/\/cytomorpholab.com\/wp-content\/uploads\/2021\/10\/Averaged-Microtubule-Asters.jpg\" class=\"attachment-large size-large wp-image-1572\" alt=\"\" srcset=\"http:\/\/cytomorpholab.com\/wp-content\/uploads\/2021\/10\/Averaged-Microtubule-Asters.jpg 293w, http:\/\/cytomorpholab.com\/wp-content\/uploads\/2021\/10\/Averaged-Microtubule-Asters-150x150.jpg 150w\" sizes=\"(max-width: 293px) 100vw, 293px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-3563b93\" data-id=\"3563b93\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-5102a3b elementor-widget elementor-widget-image\" data-id=\"5102a3b\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" width=\"293\" height=\"293\" src=\"http:\/\/cytomorpholab.com\/wp-content\/uploads\/2021\/10\/Microtubule-Aster.jpg\" class=\"attachment-large size-large wp-image-1573\" alt=\"\" srcset=\"http:\/\/cytomorpholab.com\/wp-content\/uploads\/2021\/10\/Microtubule-Aster.jpg 293w, http:\/\/cytomorpholab.com\/wp-content\/uploads\/2021\/10\/Microtubule-Aster-150x150.jpg 150w\" sizes=\"(max-width: 293px) 100vw, 293px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-70cff62\" data-id=\"70cff62\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-4401dcc elementor-widget elementor-widget-image\" data-id=\"4401dcc\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" width=\"293\" height=\"293\" src=\"http:\/\/cytomorpholab.com\/wp-content\/uploads\/2021\/10\/Microtubule-asters-montage.jpg\" class=\"attachment-large size-large wp-image-1575\" alt=\"\" srcset=\"http:\/\/cytomorpholab.com\/wp-content\/uploads\/2021\/10\/Microtubule-asters-montage.jpg 293w, http:\/\/cytomorpholab.com\/wp-content\/uploads\/2021\/10\/Microtubule-asters-montage-150x150.jpg 150w\" sizes=\"(max-width: 293px) 100vw, 293px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-b2eec89 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"b2eec89\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-ef9821c\" data-id=\"ef9821c\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-ac05ce3 elementor-widget elementor-widget-image\" data-id=\"ac05ce3\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" width=\"293\" height=\"293\" src=\"http:\/\/cytomorpholab.com\/wp-content\/uploads\/2021\/10\/Microtubule-Asters.jpg\" class=\"attachment-large size-large wp-image-1574\" alt=\"\" srcset=\"http:\/\/cytomorpholab.com\/wp-content\/uploads\/2021\/10\/Microtubule-Asters.jpg 293w, http:\/\/cytomorpholab.com\/wp-content\/uploads\/2021\/10\/Microtubule-Asters-150x150.jpg 150w\" sizes=\"(max-width: 293px) 100vw, 293px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-636ab07\" data-id=\"636ab07\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-23597ab elementor-widget elementor-widget-image\" data-id=\"23597ab\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" width=\"293\" height=\"293\" src=\"http:\/\/cytomorpholab.com\/wp-content\/uploads\/2021\/10\/Microtubule-Spindle-Kip3.jpg\" class=\"attachment-large size-large wp-image-1571\" alt=\"\" srcset=\"http:\/\/cytomorpholab.com\/wp-content\/uploads\/2021\/10\/Microtubule-Spindle-Kip3.jpg 293w, http:\/\/cytomorpholab.com\/wp-content\/uploads\/2021\/10\/Microtubule-Spindle-Kip3-150x150.jpg 150w\" sizes=\"(max-width: 293px) 100vw, 293px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-77d9e3c elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"77d9e3c\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-494a709\" data-id=\"494a709\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-587e04c elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"587e04c\" data-element_type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-6038468 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"6038468\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-7f08c65\" data-id=\"7f08c65\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-cf61a5a elementor-widget elementor-widget-text-editor\" data-id=\"cf61a5a\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div style=\"direction: ltr;\">\n<div style=\"direction: ltr; margin-top: 0in; margin-left: 0in;\">\n<div style=\"direction: ltr; margin-top: 0in; margin-left: 0in;\">\n<h4>Actin-microtubule crosstalk<\/h4>\nActin and microtubule networks interact by many ways including common signaling pathways, specific crosslinkers or via less specific steric interactions. We currently work on the reconstitution of such interactions and their contribution to the establishment of coherent heterogeneous cytoskeleton networks architectures.\n\n<\/div>\n<\/div>\n<\/div>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-d3a8f09 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"d3a8f09\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-c786335\" data-id=\"c786335\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-12ed514 elementor-widget elementor-widget-image\" data-id=\"12ed514\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" width=\"293\" height=\"293\" src=\"http:\/\/cytomorpholab.com\/wp-content\/uploads\/2021\/10\/Actin-MT-crosstalk.jpg\" class=\"attachment-large size-large wp-image-1579\" alt=\"\" srcset=\"http:\/\/cytomorpholab.com\/wp-content\/uploads\/2021\/10\/Actin-MT-crosstalk.jpg 293w, http:\/\/cytomorpholab.com\/wp-content\/uploads\/2021\/10\/Actin-MT-crosstalk-150x150.jpg 150w\" sizes=\"(max-width: 293px) 100vw, 293px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-b8640cf elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"b8640cf\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-016e57e\" data-id=\"016e57e\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-938d3a5 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"938d3a5\" data-element_type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Research IN VITRO IN CELLS TOOLS In Vitro Actin and Microtubule Networks Geometry Actin networks Actin is an asymmetric protein that can self-assemble to form polarized actin filaments. Actin filaments can interact to form actin networks. Actin networks can self-organize into two main types of structures in cells: bundles (or fibers) made of aligned long [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"http:\/\/cytomorpholab.com\/index.php\/wp-json\/wp\/v2\/pages\/1540"}],"collection":[{"href":"http:\/\/cytomorpholab.com\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"http:\/\/cytomorpholab.com\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"http:\/\/cytomorpholab.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/cytomorpholab.com\/index.php\/wp-json\/wp\/v2\/comments?post=1540"}],"version-history":[{"count":47,"href":"http:\/\/cytomorpholab.com\/index.php\/wp-json\/wp\/v2\/pages\/1540\/revisions"}],"predecessor-version":[{"id":4346,"href":"http:\/\/cytomorpholab.com\/index.php\/wp-json\/wp\/v2\/pages\/1540\/revisions\/4346"}],"wp:attachment":[{"href":"http:\/\/cytomorpholab.com\/index.php\/wp-json\/wp\/v2\/media?parent=1540"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}